The weeklong auction begins Monday night, just after the episode featuring the pop star is set to air. Spears plays a flirty receptionist who falls for the show's main character.
A half-dozen Spears-worn items will be available, including a navy print Juicy Couture dress, a yellow Nannette Lepore dress and a cream Nannette Lepore cardigan with blue flower details.
CBS and the show's producer, 20th Century Fox Television, are sponsoring the auction.
