James ran for scores from 1, 4 and 58 yards and had Stanford (9-1, 7-1) defenders slipping all over a slick field. The Ducks (9-1, 7-0) ended the nation's best winning streak at 17 games -- which the Cardinal began after a loss in Eugene more than a year ago -- and can clinch the league's North Division crown over Stanford with a win in one of their final two games.
Luck threw for 271 yards and three touchdowns with two interceptions and a fumble. Stanford had five total turnovers.
