The accident happened at Highway 180 and Academy before 9 a.m. on Tuesday morning. Investigators said the ambulance was driving with its siren on when it collided with a pickup truck.
The driver of the truck and both paramedics suffered minor injuries from the crash, but all three were transported to local hospitals to be checked out.
Both the ambulance and pickup truck are said to be totaled. Investigators say the cause of the crash is still under investigation.