Many who took to Twitter during the game were surprised when they couldn't tweet.
The outage began just before 8 p.m. and most Twitter users were able to access the social media site again in just under 30 minutes.
Twitter tweeted at about 8:35 p.m. that they were aware of users experiencing issues and were working to resolve the problem.
The Los Angeles Lakers official Twitter account also crashed during the game.
Sorry about that, everybody.— Los Angeles Lakers (@Lakers) April 14, 2016
Kobe got too hot for the Twitter servers.
Did we miss anything?— Los Angeles Lakers (@Lakers) April 14, 2016
There was no official word on whether the amount of activity surrounding Bryant's final game caused the disruption.