It happened just before 8 p.m. Monday night at 23rd and K Streets.
Merced Police say they were called to the area for a possible stabbing. When they arrived on the scene, they found the 25-year-old man lying on the sidewalk suffering from a stab wound.
A life flight helicopter took the man to a Modesto hospital where he later died.
Merced Police tell Action News they have no suspects at this time.