The show's creator Ryan Murphy said on Tuesday that he expects Spears to have a role in an episode that is "reverential about her." Murphy also said on Ryan Seacrest's radio show that he admires how the singer has turned herself around.
Spears, best known for pop hits like "Toxic" and "Baby One More Time" has spent years splattered across the tabloid pages for everything from high-profile hospitalizations to bouts of erratic behavior, like taking a baseball bat to a car or shaving her head.
In the "Glee" episode, singers at the dentist's office under anesthesia hallucinate about Spears and being like her. Murphy said the episode will feature Spears' music but won't touch on her personal life.
"We're handling Britney with kid gloves," he said.
AP contributed to this report.