Officers served a search warrant in a house on Ashby road near Fern Street Friday.
Once inside, they say they found 24-year-old Robert Christensen and 40-year-old Santiago Delgado in a back bedroom in a cloud of meth smoke.
An 11-year-old boy and a 9-year-old girl were in the home's living room.
Their mother, 32-year-old Yolanda Birreuta, and another woman, 35-year-old Misty Mudget were also taken into custody.
All of the suspects face charges of maintaining a residence for the purpose of selling narcotics. The mother and the two men also face child endangerment charges.