The students were on their way to Central High's West Campus when their school bus was rear ended.
The school bus was hit at a stop sign at Belmont near Brawley in West Central Fresno just before 7 a.m. Thursday morning.
The California Highway Patrol tells Action News the woman driving the vehicle that hit the bus was under the influence of drugs and was arrested.
Six students had minor injuries and were taken to the hospital for observation.