The Monreal family turned out in matching shirts to show their spirit.
"We started this last year and thought it was a good way to start thanksgiving and start a lot of excitement, that camaraderie already and we get to enjoy the day later," Turkey Trot participant, Christina Monreal said.
Besides the fun many came out to try to burn some calories.
"Makes me feel a lot less guilty about turkey and wine later," Monreal said.
The calorie control council estimates Americans will eat 4,500 calories during their Thanksgiving celebrations. These runners will probably burn around 300 calories on their three mile run.
Action News Reporter: "Do you think any of these people are making a dent on that calorie count today by?"
Turkey Trot participant Kevin Poythress: "Maybe a few, but probably not."
For many the run is a way to show off the most unique, strange, festive and spirited costumes.
"They asked me if I would want to wear a tutu.…..Okay I said hey we wear tutus and they didn't think I was serious, so I wore a tutu. The bow is new," Turkey Trot participant Chris Bennett
And in true Thanksgiving tradition, some people hit the field to play football.
Fresno High was bustling Thursday morning with families and friends.
"We meet here every thanksgiving at 9 o'clock and we've been doing it since the late 70's," Sam Fernandez from Fresno said.
The men say although the times have changed and the game has expanded to include their kids, they are grateful to spend time together and give thanks.