Perry died just days after suffering a massive stroke at age 52, his publicist announced on Monday.
Shannen Doherty and Jennie Garth, who played Brenda and Kelly, two of Perry's character's love interests on 90210, each spoke to People Magazine about their decades-long friendship.
"I am in shock. Heartbroken. Devastated by the loss of my friend. I have so many memories with Luke that make me smile and that are forever imprinted on my heart and mind," Doherty said. "I will miss him everyday. Every minute. Every second."
"My heart is broken. He meant so much to so many," Garth told People. "Such a very special person. I share my deep sadness with his family and all who loved him. Such a terrible loss."
Another 90210 co-star, Ian Ziering, who played Steve Sanders, wrote on Instagram, "Dearest Luke, I will forever bask in the loving memories we've shared over the last thirty years. May your journey forward be enriched by the magnificent souls who have passed before you, just like you have done here for those you leave behind. God please give him a seat close to to you, he deserves it."
Riverdale cast and crew
Lili Reinhart, who plays Betty Cooper on Riverdale, wrote that she can't believe Perry is gone.
I’m finding it hard to grasp that he will no longer be around to give long hugs and share his wisdom and kindness with all of us.— Lili Reinhart (@lilireinhart) March 4, 2019
I’m thinking of his family. His children.
I pray for them to heal and find peace in this devastating loss.
Riverdale co-star Molly Ringwald wrote, "My heart is broken."
My heart is broken. I will miss you so much Luke Perry. Sending all my love to your family. ❤️ #LukePerry— Molly Ringwald (@MollyRingwald) March 4, 2019
The writers on the show shared this message.
Luke Perry... you were a joyful and vibrant soul. You will be missed but most certainly your legacy will be remembered forever. Rest in love and peace, friend. #Riverdale— Riverdale Writers Room (@RiverdaleWriter) March 4, 2019
They said in their Twitter bio that the show's third season, which is currently airing, would be dedicated to Perry.
Other celebrity reactions
Actor Colin Hanks shared a story of how he witnessed Perry come to the rescue when two children were acting rowdy on a plane. Hanks described how Perry came back from first class, wearing sunglasses, and gave the children a balloon.
"He ties it off, hands it off like he's holding out a sword to a king. Kneeling, Head down, arms up. Kids calm down in milliseconds," Hanks wrote.
Hanks said Perry was kind when the two spoke about their work after the flight, and he told Hanks he always keeps balloons around, just in case.
Leonardo DiCaprio, who worked with Perry for the upcoming film Once Upon A Time in Hollywood, remembered Perry as "incredibly talented."
Luke Perry was a kindhearted and incredibly talented artist. It was an honor to be able to work with him. My thoughts and prayers go out to him and his loved ones.— Leonardo DiCaprio (@LeoDiCaprio) March 4, 2019
RELATED: A look back at Luke Perry's career
Others in the industry also reflected on Perry's legacy and sent thoughts to his friends and family.
I don’t understand how he’s gone.— Alyssa Milano (@Alyssa_Milano) March 4, 2019
His soul always shined so bright. His smile. His talent. His kindness. He was always the coolest person in the room.
Rest with the angels, sweet Luke. I will never forget you. pic.twitter.com/17AzJD491m
Luke Perry was a great actor and truly one of a kind. Watching him on 90210 was one of the reasons why I wanted to move to LA. Thinking of his family and friends on and off the set. Rest in peace.— Ryan Seacrest (@RyanSeacrest) March 4, 2019
L.P.— Charlie Sheen (@charliesheen) March 4, 2019
your giant heart,
enchanted so many
with brilliant aplomb.
R.I.P good sir.
to have known you
all of these years.
RIP Luke Perry. In high school we all wanted to be as cool as you.— Bryan Greenberg (@bryangreenberg) March 4, 2019
Dear Liuke ..love love and my heart is so sad I’m sending love to your family and Alexis is waiting for you ,you will laugh and dance God bless you 🙏🏿🙏🏿🙏🏿😇— Rosanna Arquette (@RoArquette) March 4, 2019