Fire crews responded to a home on Belmont and Marks Avenues shortly before 3:30 am.
The house was gated, and officials said the house was lived in up until about two weeks ago.
Firefighters did a rapid search through the house, and officials said no one was inside the house at the time.
PG&E crews disconnected a power line after it dropped onto the property.
No one was hurt.
The flames destroyed the house.
The cause of the fire is still under investigation.