The truck was hauling 80,000 pounds of garbage that spilled onto the highway.
The CHP says the big rig driver was headed for Kettleman City, hauling trash from a Kings County dump.
For unknown reasons, he overturned while on the curved on-ramp that connects northbound SR-43 and westbound SR-198. The wreckage blocked both westbound lanes.
The driver complained of some pain and was taken to Adventist Medical Center in Hanford as a precautionary measure.
No other vehicles were involved in this crash.
Traffic on westbound SR-198 was forced to make a short detour that put drivers onto the off-ramp to SR-43 and right back onto the freeway.