The crash happened in the area of R Street and 18th in Merced around 3:45 pm.
The three-year-old girl was walking with her mom and siblings along an intersection when a driver ran a red light then struck the child.
The child was unresponsive and was life flighted to Valley Children's Hospital.
Police have a bit of video and based on that, they are looking for a late 90's to early 2000's maroon Honda Accord.
Stay with Action News on this developing story.