Smittcamp was the former CEO of foods product company Lyons Magnus and was co-owner of fruit company Wawona Packing.
He passed away Thursday afternoon at the age of 79.
Smittcamp was also well known as a philanthropist, including donating millions to Community Medical Centers, and as a major political donor.
Several Valley leaders reacted to the news with sadness.
Senator Andreas Borgeas called Smittcamp a 'titan and pillar' of the community.
Fresno Mayor Jerry Dyer released a statement honoring a man he said was his mentor, trusted advisor, and dear friend.
Rep. Jim Costa wrote about Smittcamp's enthusiasm for the things he loved best - his family, California agriculture, and Fresno State.
"Bob's leadership skills and business sense were respected by those who knew him. In a life well-lived, he made a difference and will be missed," Costa wrote.