Fresno police spent hours investigating the collision that happened just after 1 a.m.
Chief Jerry Dyer tells Action News 25-year-old Fidencio Rodriguez-Florez blew through a red light on Ashlan and T-boned the other car as it tried to make a turn onto Ashlan on a green light.
The victim suffered severe injuries and was listed in critical condition.
Dyer says police arrested Rodriguez-Florez on felony charges.
Paramedics took both drivers to the hospital for treatment.
The CHP reopened the Ashlan offramp before 9:30 a.m.