Officials say Brice Robinson stabbed his 60-year-old father, Brian Robinson, at a home in the area of Hampton and Sunnyside in east central Fresno on Sunday evening.
Brian Robinson was rushed to Community Regional Medical Center, where he died from his injuries.
Homicide detectives spoke with several witnesses and eventually took Brice Robinson into custody.
Investigators have not released a motive for the deadly attack.
Brice Robinson was booked into the Fresno County Jail with his bail set at $1 million.
Anyone with information is asked to contact the Fresno County Sheriff's Office.