The Tulare County Sheriff's Office says it happened around 4 pm near County Line Road and Road 136.
Deputies arrived at the scene and found one man shot to death. Shortly after, three other shooting victims showed up at the Delano Police Department building.
Two of those victims were airlifted to the hospital. Deputies announced later that a second victim had died at the hospital.
Anyone with information is asked to contact the Tulare County Sheriff's Office.