It happened on Floral and Alta Avenues near the Fresno and Tulare county lines.
Officers say a Para was stopped at Floral Avenue and pulled forward in front of an oncoming semi-truck. The truck driver was unable to stop and crashed into her vehicle.
The crash caused the Para's car to spin out and it collided with a second truck. She was pronounced dead at the scene.
The semi-truck driver was taken to a local hospital, but their condition has not been released.
It's unclear if the second truck driver suffered any injuries.