No additional details on the person were given.
Officials remind everyone 6 months and older to get their annual flu shot to protect themselves.
"Influenza can cause serious symptoms, particularly for those with pre-existing conditions, older adults, and young children," says Fresno County Deputy Health Officer Dr. Trinidad Solis. "This tragic and untimely death serves as a reminder that we all must take preventative actions by getting vaccinated to protect ourselves and our loved ones."
Since the beginning of October, there have been 678 flu-related deaths between the ages of 18 and 64 years old in the U.S.
Flu vaccine locations can be found here.