Piles of material are burning at the Cedar Avenue Recycling and Transfer Station near Highway 99 and Cedar Ave.
Huge plumes of smoke can be seen all throughout the city.
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Fresno City Fire officials say a third alarm has been requested and that it will be hours before the fire is completely out.
Crews are prioritizing making sure the fire doesn't spread to nearby buildings.
Medical aid calls have been suspended to provide more resources for the firefight.
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All roads in the are are closed at this time.
No injuries have been reported.
This is a developing story. Stay with Action News for updates.