It happened before 7 Sunday night in the shopping center on the southeast corner of Shaw and Feland.
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Firefighters arrived to find heavy black smoke coming from the Cigar and Cigarettes store.
A second alarm was called to get firefighters to the scene.
Crews quickly moved in to put the fire out thanks in part to technology they used in the sky.
The building also included AT&T and Cricket Wireless.
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No one was injured, but power is shut off in the entire building.
Officials say the businesses will likely be closed for a while.
The cause of the fire remains under investigation.