It all started during the morning commute, with one driver losing her life.
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A dense fog advisory was in effect with thick fog along Highway 152.
The CHP says this was likely a factor in several crashes, involving numerous semi-trucks and dozens of cars.
In the first crash, at about 8:30 am, a woman died when she ran into the trailer of a semi-truck.
The driver of the truck was crossing the highway on Road 9.
A witness said other cars then ran into the woman's car.
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She died at the scene.
She was later identified as 18-year-old Sarai Baldovinos.
The CHP says when it's foggy, expect traffic to be stopped ahead of you.
At about 10 am, a section of eastbound 152 was completely snarled when more than three semis, several cars, and even an armored car collided near Avenue 11.
It took hours to clear the wreckage.
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A tow truck company owner said it was a struggle to get to the scene to help.
Our action news crew saw at least five crashes.
The CHP said several are still under investigation.