Officials say 70-year-old Agustina Cano-De Arambula of San Joaquin was killed just before 9:30 p.m. Wednesday at Manning and Adams Avenues, east of the city of San Joaquin.
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The California Highway Patrol says a 32-year-old man was behind the wheel of a semi-truck hauling grapes in a vineyard.
It was when he was turning left onto Manning out of the field when officers say he drove into the path of an SUV The car and semi collided.
The CHP says both the 72-year-old driver and Cano-De Arambula suffered major injuries.
Cano-De Arambula was flown to the hospital but died from her injuries.
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The driver of the semi was not hurt.
The crash remains under investigation but the CHP says alcohol or drugs were *not a factor.