Firefighters responded to calls of a fire at the Kwik Korner on Marion and Sierra streets around 5:40 p.m. Saturday.
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Kingsburg Fire was the first to arrive on scene and learned workers at the station's mini-mart tried to use extinguishers to put out a small fire in the back room.
Firefighters evacuated the building and then went inside to track down the source of the fire. Crews could not find the origin of the fire and called for more resources.
As backup arrived, the flames grew and were visible on the roof of the mini-mart.
Crews from Selma, Fresno County, Kings County, Tulare County and Reedley joined in the fight.
Firefighters tried to stop the blaze from inside and outside the store until they determined the building was unsafe.
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The building collapsed just before 6:30 p.m. after crews moved to fight the flames from the outside.
It's unknown if anyone was hurt.
The building housed three separate businesses, according to fire officials.
The public is asked to stay away from the area as crews work to put out the flames.
Stay with ABC30 for the latest details on this developing story.