Officers say it started around 9 am Sunday near D and Bush Streets.
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Authorities were searching for Brandon Grissom on domestic violence-related charges when they say he barricaded himself inside a hotel room.
The hotel was evacuated and officers set up a perimeter around the property.
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The 27-year-old suspect eventually came outside and was quickly detained.
He's now booked on several counts, including illegally possessing an assault weapon and child endangerment.