It happened a little after 3 am on January 5 at a home on Monreal Road near Avenue 15 in the Madera Ranchos area.
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The sheriff's department says a man called and said someone had broken into his home through the back door while he was home.
Deputies arrived and found there had been a struggle between the homeowner and the alleged intruder.
That man lost consciousness and despite efforts to revive him, he died at the scene.
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His identity has not yet been released.
An autopsy will be conducted to determine a cause of death.
No arrests have been made at this time.