"We are going to have every available officer out on the roadway," says Madera CHP Officer Javier Ruvalcaba. "They are going to be looking for aggressive and impaired drivers."
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Last Super Bowl Sunday, the CHP says five people were killed and 105 were hurt in alcohol-involved crashes on California roads
That same day, CHP officers made 229 DUI arrests.
Officer Ruvalcaba says Madera CHP has seen more DUI crashes since January 1 than what's typical for the start of the year.
"This is unpredictable," he said. "These crashes are happening all around the county, county roads, freeways."
He says most of the deadly crashes in the Madera area are caused by DUI drivers.
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"Special units that have been going throughout the Central Valley, highway patrol units that have been targeting areas," he said.
The most recent victim -- 49-year-old Patricia Vargas -- a mother of five and grandmother of four.
CHP says 33-year-old Miguel Hernandez was driving north on Road 27 before quickly turning left onto Avenue 17 in Madera County.
Patricia swerved to avoid hitting him and into oncoming traffic, hitting a trailer truck head-on.
Patricia's family says she, her daughter and another passenger were headed to the grocery store to pick up a loaf of bread around 6 Wednesday evening when they crashed.
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The CHP says Patricia's 11-year-old daughter and another adult passenger were taken to the hospital. The family says they are both out of the ICU now and are going to be okay.
Hernandez was booked into jail on multiple charges, including a DUI with three priors and murder.
The CHP is asking people to pay attention to drivers on the road who could be under the influence.
"It's an emergency," Ruvalcaba said. "It's a true emergency, so call 911. We want to hear from you."