The accident happened around 10 pm in the area of Shields and Maple.
Fresno police say a man in his 40s was being chased by two people when he ran into the roadway and was hit by a vehicle.
The man is expected to recover from his injuries.
It's currently unclear what happened leading up to the chase.
The driver pulled over after the crash and has been cooperating with officers.
Stay with Action News for the latest updates on this developing story.