Fire officials responded to reports of the fire in the area of Road 159 and Avenue 296, near Farmersville, about 8 in the morning.
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As firefighters worked to put out the fire, they discovered the two victims who were already dead.
Fire investigators and Tulare County Sheriff's deputies are investigating the incident. They say the fire appears to have been accidental in nature but remains under investigation.
Authorities have not yet identified the victims.