The Kern County Sheriff's Office said 150 people attended a house party on Stephens Drive in South Bakersfield after a social media post was widely spread.
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They said some of the partygoers, most between 15 and 18 years old, were uninvited and a disagreement escalated into gunshots being fired.
Authorities said that suspects riding in a car used at least two guns to fire into the crowd and other partygoers returned fire at the car just before 1 a.m.
There were 14 people hit in the crossfire, authorities said.
Two of those shot are in critical condition and at least one person was flown to a Fresno hospital for treatment.
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No arrests have been made.
Authorities believe there are partygoers who know the identities of the shooters and are calling for witnesses to come forward.
The suspects were described as African-American males ranging from 17 to 19 years old.