The section of road had been shut down since Tuesday after a major crash overturned a propane truck.
The closed portion of Friant at Willow Avenue reopened around 6 pm Thursday, which was a relief for drivers who had been forced to take a detour.
Clean-up crews spent days working to remove the highly flammable gas and prevent a fire in the surrounding dry brush.
The propane truck flipped on its side Tuesday night when a car pulled into its path.
Two people in the car suffered serious injuries.
The truck driver was also hurt.