Firefighters were called to the house on Chestnut and G streets just before 10 o clock on Friday night.
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They arrived and found large flames from a vacant house fire had spread to three neighboring homes.
One of those homes was a complete loss while the other two suffered moderate damage.
No injuries were reported and the cause of this fire remains under investigation this morning.
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The Red Cross is now assisting the families who lost their homes in this fire.