Fresno Police responded to the Shell gas station near Maple and Jensen Avenues after 1:00 a.m.
Officers found a man in his 20s suffering from multiple gunshot wounds and was taken to Community Regional Medical Center.
Witnesses told police the victim was with a woman and say he was involved in a disturbance with another group of men.
Officers say that the group left in unknown cars.
Anyone with information is asked to call the Fresno Police Department.