It happened on the highway just north of Clinton Avenue.
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Officials say seven vehicles were involved in the crash, including a big rig. Investigators believe the collision was weather-related, and drivers were going too fast.
The truck jack-knifed while trying to avoid crashed vehicles, blocking the southbound lanes of the highway. Traffic was backed up to Shaw Avenue for about an hour.
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The lanes have since reopened.
Authorities say some people were taken to the hospital with complaints of pain.
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