Officers received a call about a man suffering from a gunshot wound at a home on Pryor Drive and Richelle Avenue around 1:00 a.m.
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The call was from a witness at the home.
Fresno Lt. Steve Card says once officers arrived at the scene, they got everyone out of the house and conducted a search for a victim.
Card says a man in his 30s was found in the backyard with a gunshot wound and pronounced dead at the scene.
Several people were at the home and cooperated with officers.
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Statements and evidence pointed to a suspect who was detained.
Police say the suspect and victim knew each other and say both had been drinking and involved in a physical altercation leading up to the shooting.
It's unclear what triggered the altercation.
If you have any information, you can call Fresno Police.