All southbound lanes from Vista Del Lago Road to Templin Highway will be shut down starting at 10 p.m. until Sunday, April 2 at 8 a.m.
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All northbound lanes will remain open.
Interstate 5 will close again Sunday night at 11 p.m. and reopen Monday morning, April 3 at 5 a.m.
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Drivers can take Highway 138 to Highway 14 as a detour.
Stay with ABC30 for the latest details on this developing story.