Hazmat crews are on the scene at Orange and 4th Street in Corcoran cleaning up chlorine gas leaking at a nearby water treatment plant.
Caltrans also shut down roadways on Highway 43 at Orange.
Officials estimate the closure to last for the next hour or so.
In the meantime, if you are traveling in that area, you can expect delays and are urged to use a different route.
Traffic is currently being directed off the highway at Santa Fe.