Police say 21-year-old Vallejo resident Kelsey Mariah Cambridge of Vallejo has been charged with one count of vehicular manslaughter and one count of running a red light.
On Sunday around 2 p.m., police say Cambridge ran a red light on Taylor St. at O'Farrell St., in the Tenderloin and then plowed into the couple.
After hours of questioning, San Francisco police walked Cambridge from Hotel Spero into the back of a waiting squad car around 7:30 pm.
"We do not know if it was in autonomous mode or what type of mode or if she was in control of the vehicle," said SFPD Traffic Division Sgt. Frank Harrell.
What police do know, is that after running the red light, the Tesla driver broadsided a Mini Cooper, and then hit the married couple who were walking in the crosswalk.
The husband, 39-year-old Benjamin Dean, was killed. His wife was taken to San Francisco General Hospital, where she has non life-threatening injuries.
The couple is from Clovis and the wife's Facebook page indicates they were in San Francisco celebrating their anniversary.
Police say Cambridge was cooperating with them and that drugs and alcohol do not appear to be a factor.
KGO-TV contributed to this report.