Among those injured Friday are a school resource officer and a sophomore baseball player.
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Seventeen-year-old Dimitrios Pagourtzis was being held on a capital murder charge after authorities say he fatally shot 10 people and wounded at least 10 others at his high school in Santa Fe, about 30 miles (50 kilometers) southeast of Houston.
Here are some of their stories:
CYNTHIA TISDALE
Family members confirmed that substitute teacher Cynthia Tisdale was among the victims killed in the shooting.
Tisdale's niece, Leia Olinde, said Tisdale was like a mother to her and helped her shop for wedding dresses last year.
"She helped me put it on, she helped fix my hair," Olinde said through tears.
"She was wonderful. She was just so loving," said Olinde, 25. "I've never met a woman who loved her family so much."
She said Tisdale was married to her husband for close to 40 years and that the two had three children and eight grandchildren.
Tisdale's house was the center for family gatherings, and she loved cooking Thanksgiving dinner and decorating her house, Olinde said.
Olinde's fiance, Eric Sanders, said of Tisdale that "words don't explain her lust for life and the joy she got from helping people."
PHOTO: Chris Stone among victims confirmed dead
The Pakistan Embassy in Washington, D.C., confirmed on their Twitter page that exchange student Sabika Sheikh was also killed in the attack.
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The Pakistani foreign exchange student is among those killed in the shooting, according to a leader at a program for foreign exchange students and the Pakistani Embassy in Washington, D.C.
Megan Lysaght, manager of the Kennedy-Lugar Youth Exchange & Study Abroad program (YES), sent a letter to students in the program confirming that Sabika Sheikh was killed in the shooting.
"Please know that the YES program is devastated by this loss and we will remember Sabika and her families in our thoughts and prayers," Lysaght wrote.
She said the program would be holding a moment of silence for the girl, who is pictured beaming in a shirt that says "Texas" in a photo being shared on social media.
Lysaght declined further comment when contacted by The Associated Press and referred calls to a State Department spokesman.
The Pakistan Embassy in Washington, D.C., identified Sabika as a victim of the shooting on Twitter and wrote that "our thoughts and prayers are with Sabika's family and friends."
The Pakistan Association of Greater Houston said on Facebook that Sabika was due to go back home to Pakistan for Eid al-Fitr, a three-day holiday that marks the end of the holy Muslim month of Ramadan.
"May Allah bless her soul and may she RIP," the statement said.
Suspect Dimitrios Pagourtzis is in custody, and a second person has been detained following the fatal shooting.
JOHN BARNES
School police officer John Barnes was shot in the arm when he confronted the gunman.
A bullet damaged the bone and a major blood vessel around Barnes' elbow, which required surgery to repair, said David Marshall, chief nursing officer at the University of Texas Medical Branch. He said Barnes was in stable condition.
Barnes was the first to engage Pagourtzis, according to Marshall.
ROME SHUBERT
Sophomore baseball player Rome Shubert says the gunman walked into his classroom and tossed something onto desks.
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Shubert told the Houston Chronicle that he then heard "three loud pops" before the attacker fled into the hall. Shubert says he realized he'd been wounded as he was running out the back door.
Shubert says he was hit in the back of his head with what he says was a bullet, but that it "missed everything vital." He also tweeted that he was OK and stable.
NUMEROUS VICTIMS AT LOCAL HOSPITALS
A Santa Fe ISD police officer, John Barnes, was shot in the upper arm near his chest and is currently undergoing surgery.
According to the chief nursing officer at UTMB, David Marshall, there are three victims at the hospital, including the police officer.
Marshall said during a press conference that two adults and one minor were transported to the facility for treatment.
Marshall released information about the three victims at UTMB. He said that the 16-year-old shot was transported to the hospital with a gunshot wound to the leg. He's in stable condition.
The third victim at the hospital is a woman who sustained a gunshot wound to the leg. She's also in stable condition in the operating room.
School police officer John Barnes was shot in the arm when he confronted the gunman.
A bullet damaged the bone and a major blood vessel around Barnes' elbow, which required surgery to repair, said David Marshall, chief nursing officer at the University of Texas Medical Branch. He said Barnes was in stable condition.
Barnes was the first to engage Pagourtzis, according to Marshall.
Sophomore baseball player Rome Shubert says the gunman walked into his classroom and tossed something onto desks.
Shubert told the Houston Chronicle that he then heard "three loud pops" before the attacker fled into the hall. Shubert says he realized he'd been wounded as he was running out the back door.
Shubert says he was hit in the back of his head with what he says was a bullet, but that it "missed everything vital." He also tweeted that he was OK and stable.
The Associated Press contributed to this report.