The vehicle caught fire on 16th Street between R and V at about 9 am.
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Crews found the motorhome engulfed in flames.
Officials say one person was found burned at the scene and hospitalized. The other person was not injured.
Three dogs were killed in the fire.
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The vehicle has been moved off the road.
The cause of the fire is under investigation.
EDITOR'S NOTE: The video above is from a previous broadcast and will be updated.