Detectives say they believe 26-year-old Joel Rodriguez shot and killed 30-year-old Steven Montano on New Year's Day.
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The shooting happened at the Parks at Fig Garden Apartments on Fruit and Saginaw.
Montano was rushed to a local hospital, where he died a short time later.
Police confirmed Rodriquez was the suspect in Tuesday's police chase that ended with an officer crashing into a fire hydrant.
RELATED: Fresno police officer crashes into fire hydrant during chase
Police are asking for the public's help finding Rodriquez.
Anyone with information on his location is to call Fresno Police detectives at (559) 621-2449. Call Valley Crime Stoppers at 498-STOP (7867) to do so anonymously.