Eric Heard is accused of murdering his sister and nephew.
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Police say he shot 33-year-old Fanchon Moore and 17-year-old Antonio Rodriguez after an argument at a home on Weathermaker and Winery Avenues in east central Fresno.
Officers arrested Heard last week on a previous misdemeanor warrant, but the Fresno County district attorney's office has since filed the two murder charges.
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He's due back in court next Monday for a preliminary hearing.
Because this is a double murder case, Heard could face the death penalty.