It happened around 10 pm on East Samson between MLK Jr. Boulevard and Clara Avenue.
Police say they arrived to find a man in the street with multiple gunshot wounds. He was pronounced dead at the scene.
Officers say there was a party happening nearby, but there is no word if it had anything to do with the shooting on Samson.
Police say shell casings were found at the scene.
Anyone with more information is asked to contact the Fresno Police Department.