Portland Timbers to face San Jose Earthquakes in U.S. Open Cup

The Portland Timbers will host the San Jose Earthquakes as MLS teams enter the U.S. Open Cup in the fourth round.

The Timbers-Earthquakes matchup is the only one involving two MLS teams.

Most MLS clubs were matched up with lower-division teams from their regions, though many matchups are yet to be fully set before their opponents conclude the third round on June 1.

Among the possible matchups are New York City FC hosting the NASL's New York Cosmos, as well as FC Dallas playing at Rayo OKC.

Soon-to-be MLS franchise Minnesota United could play host to Sporting Kansas City, while the Seattle Sounders could face the Sacramento Republic, which is under strong consideration to join the top flight.

The LA Galaxy were drawn against the winner of two local amateur clubs from the United States Adult Soccer Association -- the L.A. Wolves and La Moquina.

Games to be played June 15:

LA Galaxy

v

L.A. Wolves/La Moquina

Philadelphia Union

v

Harrisburg City/Chattanooga

D.C. United

v

Richmond Kickers/Fort Lauderdale

Columbus Crew SC

v

FC Cincinnati/Tampa Bay Rowdies

Louisville City/Chicago Fire

v

Chicago Fire/Indy Eleven

Saint Louis FC/Minnesota United

v

Sporting Kansas City

Rayo OKC/FC Dallas

v

FC Dallas/Oklahoma City Energy

Houston Dynamo

v

San Antonio/Des Moines Menace

Colorado Rapids

v

CS Switchbacks/Arizona United

Seattle Sounders

v

Kitsap Pumas/Sac. Republic

Portland Timbers

v

San Jose Earthquakes

New York City FC

v

NYPF/Jersey Express/N.Y. Cosmos

N.Y. Red Bulls/Rochester Rhinos

v

Landsdown Bhoys/N.Y. Red Bulls

Jacksonville Armada/Orlando City

v

Orlando City/The Villages

Wilmington Hammerheads/Miami

v

Real Salt Lake

Carolina Railhawks/Charlotte Independence

v

New England Revolution