It was a rough return for Quick as he gave up six goals in 29 shots before being pulled for Jack Campbell with 10:40 left in a 7-2 loss at Staples Center.
Quick played in the Kings' season opener, but he missed the next five games because of a lower-body injury suffered in practice. Campbell played all five games in Los Angeles' net during Quick's absence.
Quick is beginning his 11th season as the Kings' starting goalie. The 2012 Conn Smythe Trophy winner and two-time Stanley Cup champion won his second William H. Jennings Trophy last season as the goalie for the team with the NHL's fewest goals allowed.
Quick's 293 career victories are easily the most in Kings history.
Forward Tanner Pearson was active with Kopitar out.
Information from The Associated Press was used in this report.