It happened today around 3:20am in the 2400 block of West Mount Houston.
Investigators said Ricardo Paskinel Zepata-Bernal was westbound in a maroon Nissan Pathfinder when an eastbound silver Ford Taurus driven by Arturo Salinas crossed into oncoming traffic and hit Zepata-Bernal's SUV.
It's unclear why Salinas crossed into oncoming traffic. He was dead when deputies arrived at the scene.
Officials said Zepata-Bernal was transported to a local hospital with minor injuries.
According to deputies, Zepata-Bernal exhibited signs of impairment. Blood test results are pending.