The actor appeared gaunt while sitting on the stage Friday. His attorney claims Hopper weighs less than 100 pounds and is unable to undergo chemotherapy. However, his doctor gave him the OK to appear at the star unveiling.
Surrounded by his family, the actor thanked Hollywood for being "my home and my schooling."
Viggo Mortensen, who appeared with Hopper in the 1991 film "The Indian Runner" and "Boiling Point" two years later, joined him in speaking at the ceremony.
"It is an honor to be here with all of you in welcoming Dennis today and giving him his star which he deserves," said Mortensen. "Dennis Hopper has become to be considered by many a legendary, and legendarily eccentric director and actor in the movie business. He is someone who has seemed to have regularly risen out of the ashes of self-inflicted chaos, surprising us with his originality and wit."
Jack Nicholson, David Lynch and Dwight Yoakam were also on hand to honor their friend and colleague.
Hopper filed for divorce Jan. 14 from his wife, Victoria Hopper, to end their marriage of nearly 14 years, citing irreconcilable differences. He was diagnosed with prostate cancer in October.
The two have agreed to stay 10 feet away from each other while the divorce is ongoing. She has stated in court filings that Hopper filed for divorce to cut her out of her inheritance, a claim the actor has denied.
The case is scheduled for a court hearing on April 5.
Hopper began his film career in the classic 1955 tale of teenage rebellion, "Rebel Without a Cause," developing a friendship with its star, James Dean. The two also appeared in "Giant."
Hopper has appeared in more than 150 films including 'Apocalypse Now," "Blue Velvet" and "Speed."
Hopper received a best original screenplay Oscar nomination for co-writing the script of the 1969 counter-culture road movie "Easy Rider," which he directed and starred in.
Hopper received the 2,403rd star on the Hollywood Walk of Fame.
City News Service contributed to this report.