Authorities say the child's mother, Elizabeth Escalona, was crying and hysterical when she called her own mother on Wednesday morning. When the grandmother arrived at the apartment, Joselyn Cedillo, 2, was unconscious.
The grandmother took her to the hospital, where doctors found that she had multiple internal injuries.
One of the girl's brothers said their mother kicked the child in the stomach and beat her with a belt and shoe, according to police records.
The girl was found to have glue and paint stuck to her palms and skin torn away in places.
Another sibling said Escalona dragged Joselyn by her feet from the kitchen to another part of the apartment, put glue on her hands and stuck them to the wall.
Escalona could face a sentence of up to life in prison if she's charged and convicted of injury to a child. She is being held on $500,000 bond.
Custody of the girl and her three siblings has been handed over to Child Protective Services.
The Associated Press contributed to this report.