It happened along Highway 99 north of Applegate Road.
California Highway Patrol officers said the 28-year-old driver crashed through a construction zone and slammed into a parked paving machine.
The woman died at the scene. Her name has not been released.
Officers believe alcohol was a factor. The crash is still under investigation.
Editor's Note: Authorities originally said the driver was a male in his 40s, but have since updated that information to indicate the driver was a 28-year-old female.