Tulare County Firefighters say a motorhome going south on 99, blew a tire and crashed into a tree around 6:00 Wednesday night.
The motorhome caught fire ... burning the vehicle all the way to the frame. A man and a woman were inside when it crashed. The woman was air-lifted to the hospital with major injuries. The man's injuries are unknown.
The entire freeway was closed for about an hour while emergency crews worked to clean up the accident.
